Proteintech, 66537-1-Ig, EXOC3L2 Monoclonal antibody

Size: 20ul / 150ul The EXOC3L2 (66537-1-Ig) by Proteintech is a Monoclonal antibody targeting EXOC3L2 in WB, IF/ICC, ELISA applications with reactivity to Human samples 66537-1-Ig targets EXOC3L2 in WB, IF/ICC, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: HUVEC cells Positive IF/ICC detected in: HUVEC cells Recommended dilution Western Blot (WB): WB : 1:1500-1:6000 Immunofluorescence (IF)/ICC: IF/ICC : 1:400-1:1600 Background Information The exocyst is a protein complex that ensures spatial targeting of exocytotic vesicles to the plasma membrane. Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells (PMID: 21566143). The gene of human EXOC3L2 maps to chromosome 19q13.32 and encodes a deduced 409-amino acid protein with a calculated molecular mass of about 46 kDa. Mouse Exoc3l2 gene encodes an approximately 250-amino acid protein that lacks the N-terminal domain of human EXOC3L2. Mutations in EXOC3L2 gene may be associated with Alzheimer's disease. Specification Tested Reactivity: Human Cited Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag26912 Product name: Recombinant human EXOC3L2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 16-278 aa of BC104947 Sequence: GTLRGLEDECVTDVKAQTRAALLRVLQEDEEHWGSLEDQPSSLAQDVCELLEEHTERAPRISQEFGERMAHCCLGGLAEFLQSFQQRVERFHENPAVREMLPDTYISKTIALVNCGPPLRALAERLARVGPPESEPAREASASALDHVTRLCHRVVANLLFQELQPHFNKLMRRKWLSSPEALDGIVGTLGAQALALRRMQDEPYQALVAELHRRALVEYVRPLLRGRLRCSSARTRSRVAGRLREDAAQLQRLFRRLESQAS Predict reactive species Full Name: exocyst complex component 3-like 2 Calculated Molecular Weight: 46 kDa Observed Molecular Weight: 46 kDa GenBank Accession Number: BC104947 Gene Symbol: EXOC3L2 Gene ID (NCBI): 90332 RRID: AB_2881900 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q2M3D2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.