Product Description
Size: 20ul / 150ul
The SMYD4 (66874-1-Ig) by Proteintech is a Monoclonal antibody targeting SMYD4 in WB, ELISA applications with reactivity to Human samples
66874-1-Ig targets SMYD4 in WB, ELISA applications and shows reactivity with Human samples.
Tested Applications
Positive WB detected in: MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Background Information
SMYD4, also named as SET and MYND domain-containing protein 4, is a 804 amino acid protein, which contains 1 MYND-type zinc finger and 1 SET domain. SMYD4 belongs to the class V-like SAM-binding methyltransferase superfamily. SMYD4, as a potential tumor suppressor, plays a critical role in breast carcinogenesis at least partly through inhibiting the expression of Pdgfr-alpha, and could be a novel target for improving treatment of breast cancer. SMYD4 is a muscle-specific transcriptional modulator involved in development.
Specification
Tested Reactivity: Human
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag11552 Product name: Recombinant human SMYD4 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 201-578 aa of BC035077 Sequence: KDSLTESFPAALAKTLEDAALREENEQLSNASSSIGLCVDPLKGRCLVATKDILPGELLVQEDAFVSVLNPGELPPPHHGLDSKWDTRVTNGDLYCHRCLKHTLATVPCDGCSYAKYCSQECLQQVWELYHRTECPLGGLLLTLGVFCHIALRLTLLVGFEDVRKIITKLCDKISNKDICLPESNNQVKTLNYGLGESEKNGNIVETPIPGCDINGKYENNYNAVFNLLPHTENHSPEHKFLCALCVSALCRQLEAASLQAIPTERIVNSSQLKAAVTPELCPDVTIWGVAMLRHMLQLQCNAQAMTTIQHTGPKGSIVTDSRQVRLATGIFPVISLLNHSCSPNTSVSFISTVATIRASQRIRKGQEILHCYGPHKS Predict reactive species
Full Name: SET and MYND domain containing 4
Calculated Molecular Weight: 804 aa, 89 kDa
Observed Molecular Weight: 85-89 kDa
GenBank Accession Number: BC035077
Gene Symbol: SMYD4
Gene ID (NCBI): 114826
RRID: AB_2882208
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein G purification
UNIPROT ID: Q8IYR2
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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