Product Description
Size: 20ul / 150ul
The FRZB (67081-1-Ig) by Proteintech is a Monoclonal antibody targeting FRZB in WB, ELISA applications with reactivity to Human, mouse samples
67081-1-Ig targets FRZB in WB, ELISA applications and shows reactivity with Human, mouse samples.
Tested Applications
Positive WB detected in: LNCaP cells, 4T1 cells, MKN-45 cells, SGC-7901 cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
Frzb (also known as sFRP3) is a member of the secreted frizzled related protein (SFRP) family, originally identified as a chondrogenic factor during bone morphogenesis (PMID: 29209231). It was subsequently shown to be a regulator in Wnt signaling, and also have a role in regulating cell growth and differentiation in specific cell types. FRZB was seen to be acting as an oncogene in some cancer, such as metastatic renal cancer.
Specification
Tested Reactivity: Human, mouse
Cited Reactivity: human
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag28147 Product name: Recombinant human FRZB protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 153-325 aa of BC027855 Sequence: IVTADGADFPMDSSNGNCRGASSERCKCKPIRATQKTYFRNNYNYVIRAKVKEIKTKCHDVTAVVEVKEILKSSLVNIPRDTVNLYTSSGCLCPPLNVNEEYIIMGYEDEERSRLLLVEGSIAEKWKDRLGKKVKRWDMKLRHLGLSKSDSSNSDSTQSQKSGRNSNPRQARN Predict reactive species
Full Name: frizzled-related protein
Calculated Molecular Weight: 325 aa, 36 kDa
Observed Molecular Weight: 36 kDa
GenBank Accession Number: BC027855
Gene Symbol: FRZB
Gene ID (NCBI): 2487
RRID: AB_2882389
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein G purification
UNIPROT ID: Q92765
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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