Proteintech, 67346-1-Ig, COX-1/Cyclooxygenase-1 Monoclonal antibody

Size: 20ul / 150ul The COX-1/Cyclooxygenase-1 (67346-1-Ig) by Proteintech is a Monoclonal antibody targeting COX-1/Cyclooxygenase-1 in WB, IF/ICC, ELISA applications with reactivity to human samples 67346-1-Ig targets COX-1/Cyclooxygenase-1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: L02 cells, K-562 cells, A431 cells, Human peripheral blood leukocyte Positive IF/ICC detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:1000-1:3000 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information PTGS1(Prostaglandin G/H synthase 1) belongs to the prostaglandin G/H synthase family and catalyzes the conversion of arachidonic acid to prostaglandin H2, which is subsequently metabolized to various biologically active prostaglandins. It is also named as COX1(Cyclooxygenase-1). There is no PTGS1 expression in fetal samples (prostate, seminal vesicles, or ejaculatory ducts), and only minimal expression in adult tissues (PMID: 10999846). PTGS1 has some isoforms with MW of 56-72 kD and PTGS1 can form homodimer. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2b Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag28280 Product name: Recombinant human PTGS1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 250-599 aa of BC029840 Sequence: KLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL Predict reactive species Full Name: prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) Calculated Molecular Weight: 599 aa, 69 kDa Observed Molecular Weight: 60-72 kDa GenBank Accession Number: BC029840 Gene Symbol: PTGS1 Gene ID (NCBI): 5742 RRID: AB_2882604 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P23219 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.