Proteintech, 67537-1-Ig, KLRB1/CD161 Monoclonal antibody

Size: 20ul / 150ul The KLRB1/CD161 (67537-1-Ig) by Proteintech is a Monoclonal antibody targeting KLRB1/CD161 in WB, ELISA applications with reactivity to human samples 67537-1-Ig targets KLRB1/CD161 in WB, IHC, IF, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: human spleen tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information CD161, also known as KLRB1 or NKR-P1A, is a type II transmembrane C-type lectin-like receptor and is expressed on the cell membrane as disulfide-linked homodimer (PMID: 8077657). It is expressed by the majority of NK cells and subsets of peripheral T cells, including both CD4+ and CD8+ T cells, and is expressed preferentially on adult T cells with a "memory" antigenic phenotype (PMID: 8077657; 22566826). Expression of CD161 correlates with the cytotoxic function of CD16+ NK cells, and ligation of CD161 with its ligand LLT1 inhibits NK cell cytotoxicity and cytokine secretion (PMID: 29686665). Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag27117 Product name: Recombinant human KLRB1,CD161 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 68-225 aa of BC114516 Sequence: KSSIEKCSVDIQQSRNKTTERPGLLNCPIYWQQLREKCLLFSHTVNPWNNSLADCSTKESSLLLIRDKDELIHTQNLIRDKAILFWIGLNFSLSEKNWKWINGSFLNSNDLEIRGDAKENSCISISQTSVYSEYCSTEIRWICQKELTPVRNKVYPDS Predict reactive species Full Name: killer cell lectin-like receptor subfamily B, member 1 Calculated Molecular Weight: 225 aa, 25 kDa Observed Molecular Weight: 32 kDa GenBank Accession Number: BC114516 Gene Symbol: CD161 Gene ID (NCBI): 3820 ENSEMBL Gene ID: ENSG00000111796 RRID: AB_2882756 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q12918 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.