Proteintech, 67592-1-Ig, TERF1 Monoclonal antibody

Size: 20ul / 150ul The TERF1 (67592-1-Ig) by Proteintech is a Monoclonal antibody targeting TERF1 in WB, ELISA applications with reactivity to human samples 67592-1-Ig targets TERF1 in WB, IF, IP, ChIP, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: K-562 cells, HEK-293 cells, Jurkat cells Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection. Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag12540 Product name: Recombinant human TERF1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 118-419 aa of BC029378 Sequence: CQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKNLFLSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED Predict reactive species Full Name: telomeric repeat binding factor (NIMA-interacting) 1 Calculated Molecular Weight: 439 aa, 50 kDa Observed Molecular Weight: 48-50 kDa GenBank Accession Number: BC029378 Gene Symbol: TERF1 Gene ID (NCBI): 7013 RRID: AB_2918494 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P54274 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.