Proteintech, 67804-1-Ig, WWP1 Monoclonal antibody

Size: 20ul / 150ul The WWP1 (67804-1-Ig) by Proteintech is a Monoclonal antibody targeting WWP1 in WB, ELISA applications with reactivity to human samples 67804-1-Ig targets WWP1 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: MCF-7 cells, HaCaT cells, HeLa cells, LNCaP cells, Jurkat cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is a multifunction protein containing an N-terminal C2 domain, four tandem WW domains for substrate binding, and a C-terminal catalytic HECT domain for ubiquitin transferring. It is also named as AIP5, Tiul1. WWP1 regulates a variety of cellular biological processes including protein trafficking and degradation, signaling, transcription, and viral budding. WWP1 has been implicated in several diseases, such as cancers, infectious diseases, neurological diseases, and aging(PMID:22051607). It has 6 isoforms produced by alternative splicing. Specification Tested Reactivity: human Cited Reactivity: human, mouse Host / Isotype: Mouse / IgG2b Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag30171 Product name: Recombinant human WWP1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-350 aa of BC036065 Sequence: MATASPRSDTSNNHSGRLQLQVTVSSAKLKRKKNWFGTAIYTEVVVDGEITKTAKSSSSSNPKWDEQLTVNVTPQTTLEFQVWSHRTLKADALLGKATIDLKQALLIHNRKLERVKEQLKLSLENKNGIAQTGELTVVLDGLVIEQENITNCSSSPTIEIQENGDALHENGEPSARTTARLAVEGTNGIDNHVPTSTLVQNSCCSYVVNGDNTPSSPSQVAARPKNTPAPKPLASEPADDTVNGESSSFAPTDNASVTGTPVVSEENALSPNCTSTTVEDPPVQEILTSSENNECIPSTSAELESEARSILEPDTSNSRSSSAFEAAKSRQPDGCMDPVRQQSGNANTET Predict reactive species Full Name: WW domain containing E3 ubiquitin protein ligase 1 Calculated Molecular Weight: 922 aa, 105 kDa Observed Molecular Weight: 95-105 kDa GenBank Accession Number: BC036065 Gene Symbol: WWP1 Gene ID (NCBI): 11059 RRID: AB_2918567 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9H0M0 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.