Proteintech, 68595-1-Ig, GABRG2 Monoclonal antibody

Size: 20ul / 150ul The GABRG2 (68595-1-Ig) by Proteintech is a Monoclonal antibody targeting GABRG2 in WB, ELISA applications with reactivity to human, mouse, rat, rabbit samples 68595-1-Ig targets GABRG2 in WB, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples. Tested Applications Positive WB detected in: rabbit brain tissue, rat brain tissue, mouse brain tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2), which is expected to be located in cell membrane and expressed in brain and retina. The calculated molecular weight of the protein is 54 kDa. This antibody can recognize the 43 kDa band of target (PMID:12091434). And it also has glycosylation modification. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Specification Tested Reactivity: human, mouse, rat, rabbit Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag5489 Product name: Recombinant human GABRG2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 42-274 aa of BC059389 Sequence: SDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGY Predict reactive species Full Name: gamma-aminobutyric acid (GABA) A receptor, gamma 2 Calculated Molecular Weight: 467 aa, 54 kDa Observed Molecular Weight: 40-54 kDa GenBank Accession Number: BC059389 Gene Symbol: GABRG2 Gene ID (NCBI): 2566 RRID: AB_3085294 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P18507 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.