Proteintech, 68602-1-Ig, INPP5E Monoclonal antibody

Size: 20ul / 150ul The INPP5E (68602-1-Ig) by Proteintech is a Monoclonal antibody targeting INPP5E in WB, ELISA applications with reactivity to Human samples 68602-1-Ig targets INPP5E in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: SH-SY5Y cells, HaCaT cells, HEK-293 cells, U-251 cells, HeLa cells Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information INPP5E(72 kDa inositol polyphosphate 5-phosphatase) converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2.In mouse, highest protein expression was in brain, heart, and testis, with lower expression in thymus and lung, and very little expression in kidney, spleen, and liver(PMID:10764818). Defects in INPP5E are the cause of Joubert syndrome type 1 (JBTS1) and mental retardation-truncal obesity-retinal dystrophy-micropenis (MORMS)(PMID:19668215). Specification Tested Reactivity: Human Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag11959 Product name: Recombinant human INPP5E protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-350 aa of BC028032 Sequence: MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPRSPLACDDCSLRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWET Predict reactive species Full Name: inositol polyphosphate-5-phosphatase, 72 kDa Calculated Molecular Weight: 644 aa, 70 kDa Observed Molecular Weight: 72 kDa GenBank Accession Number: BC028032 Gene Symbol: INPP5E Gene ID (NCBI): 56623 RRID: AB_3085298 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9NRR6 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.