Proteintech, 68674-2-Ig, CD86 Monoclonal antibody

Size: 20ul / 150ul The CD86 (68674-2-Ig) by Proteintech is a Monoclonal antibody targeting CD86 in WB, ELISA applications with reactivity to Human samples 68674-2-Ig targets CD86 in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: Raji cells, Daudi cells, Ramos cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Specification Tested Reactivity: Human Cited Reactivity: human, mouse Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD86 molecule Calculated Molecular Weight: 329 aa, 38 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: NM_175862 Gene Symbol: CD86 Gene ID (NCBI): 942 ENSEMBL Gene ID: ENSG00000114013 RRID: AB_3670400 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P42081 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.