Proteintech, 68774-1-Ig, CALCA/Calcitonin Monoclonal antibody

Size: 20ul / 150ul The CALCA/Calcitonin (68774-1-Ig) by Proteintech is a Monoclonal antibody targeting CALCA/Calcitonin in WB, IHC, ELISA applications with reactivity to human samples 68774-1-Ig targets CALCA/Calcitonin in WB, IHC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: TT cells Positive IHC detected in: human thyroid cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Immunohistochemistry (IHC): IHC : 1:500-1:2000 Background Information Calcitonin is a peptide hormone consisting of 32 amino acids, primarily synthesized by the parafollicular cells (C cells) of the human thyroid gland. It plays a crucial role in regulating calcium levels in the blood by decreasing them. Calcitonin opposes the actions of parathyroid hormone, which increases blood calcium levels. Calcitonin works through a G protein-coupled receptor, known as the calcitonin receptor, which predominantly transmits signals via the cAMP and PLC/IP3 pathways. Its primary physiological effects are on osteoclasts and the tubular epithelium of kidneys. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag26141 Product name: Recombinant human CALCA protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 26-116 aa of BC093753 Sequence: APFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP Predict reactive species Full Name: Calcitonin Calculated Molecular Weight: 141 aa, 15 kDa Observed Molecular Weight: 14 kDa GenBank Accession Number: BC093753 Gene Symbol: CALCA Gene ID (NCBI): 796 RRID: AB_3670424 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P01258 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.