Product Description
Size: 20ul / 150ul
The ATF1 (68813-4-Ig) by Proteintech is a Monoclonal antibody targeting ATF1 in WB, ELISA applications with reactivity to human, mouse, rat samples
68813-4-Ig targets ATF1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: A431 cells, HeLa cells, HT-1376 cells, K-562 cells, TF-1 cells, HSC-T6 cells, RAW 264.7 cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
TFs play a vital role in maintaining cell homeostasis by combining DNA regulatory sequences to regulate gene transcription rates. Activating transcription factor 1 (ATF1) is a member of the ATF/CREB family of transcription factors (TFs), specifically interacting with the consensus ATF/CRE site 'TGACGTCA'(PMID: 28032861). ATF1 transcriptionally regulates the expressions of target genes to mediate various cellular processes, and ATF1 effects the progression of tumors (including lung cancer, colorectal cancer,and nasopharyngeal carcinoma).
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag34935 Product name: Recombinant human ATF1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-271 aa of BC029619 Sequence: MEDSHKSTTSETAPQPGSAVQGAHISHIAQQVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSNKSV Predict reactive species
Full Name: activating transcription factor 1
Calculated Molecular Weight: 271 aa, 29 kDa
Observed Molecular Weight: 35-40 kDa
GenBank Accession Number: BC029619
Gene Symbol: ATF1
Gene ID (NCBI): 466
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein G purification
UNIPROT ID: P18846
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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