Proteintech, 69029-1-Ig, NeutraKine®IL-12 p35 Monoclonal antibody

Size: 25ug / 100ug The NeutraKine®IL-12 p35 (69029-1-Ig) by Proteintech is a Monoclonal antibody targeting NeutraKine®IL-12 p35 in ELISA, Neutralization applications with reactivity to Human samples 69029-1-Ig targets NeutraKine®IL-12 p35 in ELISA, Neutralization applications and shows reactivity with Human samples. Background Information IL-12 p35 is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.This antibody can be used to neutralize the bioactivity of IL-12 p35. Specification Tested Reactivity: Human Host / Isotype: Mouse / IgG2b Class: Monoclonal Type: Antibody Immunogen: RecombinantProtein Predict reactive species Full Name: interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) Gene Symbol: IL-12A Gene ID (NCBI): 3592 RRID: AB_3085332 Conjugate: Unconjugated Form: Lyophilized Powder Purification Method: Protein A purification UNIPROT ID: P29459 Storage Buffer: Sterile PBS, pH 7.4. Endotoxin: <0.1 EU/μg Reconstitution: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. Stability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.