Proteintech, 69034-1-Ig, NeutraKine®IL-27 Mouse McAb

Size: 25ug / 100ug The NeutraKine®IL-27 (69034-1-Ig) by Proteintech is a Monoclonal antibody targeting NeutraKine®IL-27 in Neutralization, ELISA applications with reactivity to human samples 69034-1-Ig targets NeutraKine®IL-27 in Neutralization, ELISA applications and shows reactivity with human samples. Background Information IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.This antibody is used to neutralize the bioactivity of IL-27. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: interleukin 27 Gene Symbol: IL-27 Gene ID (NCBI): 246778 RRID: AB_3670460 Conjugate: Unconjugated Form: Lyophilized Powder Purification Method: Protein G purification UNIPROT ID: Q8NEV9 Storage Buffer: Sterile PBS, pH 7.4. Endotoxin: <0.1 EU/μg Reconstitution: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. Stability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.