Proteintech, 69512-1-Ig, NeutraControl TGF beta 1 Mouse McAb

Size: 100ug The NeutraControl TGF beta 1 (69512-1-Ig) by Proteintech is a Monoclonal antibody targeting NeutraControl TGF beta 1 in IF/ICC, ELISA, Non-Neutralization applications with reactivity to human samples 69512-1-Ig targets TGF beta 1 in IF/ICC, ELISA, Non-Neutralization applications and shows reactivity with human samples. Background Information TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).This antibody is a neutralizing control antibody for TGF beta 1, the immunogen is the same as Neutrakine 69012-1-Ig but could not neutralize human TGF beta 1. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Product name: HumanKine® recombinant human TGF beta 1 protein Source: -derived, Tag: Domain: of Sequence: Predict reactive species Full Name: transforming growth factor, beta 1 Calculated Molecular Weight: 44 kDa Gene Symbol: TGFB1 Gene ID (NCBI): 7040 RRID: AB_2923690 Conjugate: Unconjugated Form: Lyophilized Powder Purification Method: Protein G purification UNIPROT ID: P01137 Storage Buffer: Sterile PBS, pH 7.4. Endotoxin: <0.1 EU/μg Reconstitution: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. Stability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.