Proteintech, 81398-1-RR, Phospho-MNK1 (Thr250/255) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-MNK1 (Thr250/255) (81398-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-MNK1 (Thr250/255) in WB, ELISA applications with reactivity to Human samples 81398-1-RR targets Phospho-MNK1 (Thr250/255) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: HEK-293T cells, HEK-293 cells, λ phosphatase treated HEK-293T cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information MNK1/MKNK1 (MAPK Interacting Serine/Threonine Kinase 1) is a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. MNK1 regulates diverse biologic processes including translation, cell proliferation, and differentiation through phosphorylation of different substrates(PMID: 29045529). Through phosphorylation MNK1 regulates the function of eukaryotic translation initiation factor 4E (eIF4E), a key player in translational control, whose expression is mostly upregulated in cancer patients. Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: MAP kinase interacting serine/threonine kinase 1 Calculated Molecular Weight: 51 kDa Observed Molecular Weight: 51 kDa GenBank Accession Number: BC002755 Gene Symbol: MNK1 Gene ID (NCBI): 8569 RRID: AB_2935427 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9BUB5 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.