Proteintech, 82796-4-RR, PI3 Kinase p110 Alpha Recombinant monoclonal antibody

Size: 20ul / 100ul The PI3 Kinase p110 Alpha (82796-4-RR) by Proteintech is a Recombinant antibody targeting PI3 Kinase p110 Alpha in WB, ELISA applications with reactivity to human, mouse, rat samples 82796-4-RR targets PI3 Kinase p110 Alpha in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HeLa cells, HEK-293 cells, COLO 320 cells, Jurkat cells, NIH/3T3 cells, mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB). Specification Tested Reactivity: human, mouse, rat Cited Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag16586 Product name: Recombinant human PIK3CA protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-355 aa of BC113601 Sequence: MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIY Predict reactive species Full Name: phosphoinositide-3-kinase, catalytic, alpha polypeptide Calculated Molecular Weight: 1068 aa, 124 kDa Observed Molecular Weight: 110 kDa GenBank Accession Number: BC113601 Gene Symbol: PIK3CA Gene ID (NCBI): 5290 RRID: AB_3086541 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P42336 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.