Proteintech, 82847-1-RR, GNRHR Recombinant monoclonal antibody

Size: 20ul / 100ul The GNRHR (82847-1-RR) by Proteintech is a Recombinant antibody targeting GNRHR in WB, ELISA applications with reactivity to Human, mouse samples 82847-1-RR targets GNRHR in WB, ELISA applications and shows reactivity with Human, mouse samples. Tested Applications Positive WB detected in: U-251 cells, MCF-7 cells, PC-3 cells, HEK-293 cells, mouse testis tissue Recommended dilution Western Blot (WB): WB : 1:2000-1:10200 Background Information GNRHR, also named GRHR, belongs to the G-protein coupled receptor 1 family. GNRHR is a receptor for GnRH that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform2 of GNRHR may act as an inhibitor of GnRH-R signaling. Defects in GNRHR are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Defects in GNRHR are a cause of fertile eunuch syndrome. The predicted unmodified molecular weight of the human GNRHR is ~38 kDa, the larger band (50-65 kDa) is likely to represent a glycosylated form of GNRHR. Specification Tested Reactivity: Human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: GnRH receptor Calculated Molecular Weight: 38 kDa Observed Molecular Weight: ~38 kDa GenBank Accession Number: NM_000406 Gene Symbol: GNRHR Gene ID (NCBI): 2798 RRID: AB_3086553 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P30968 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.