Proteintech, 83825-3-RR, ZFP64 Recombinant monoclonal antibody

Size: 20ul / 100ul The ZFP64 (83825-3-RR) by Proteintech is a Recombinant antibody targeting ZFP64 in WB, ELISA applications with reactivity to human samples 83825-3-RR targets ZFP64 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: K-562 cells, Jurkat cells, MKN-45 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information ZFP64 (also known as ZNF338) is a member of the Krüppel C2H2-type zinc finger family. ZFP64 is a coactivator of Notch1, mediating mesenchymal cell differentiation. ZFP64 expression was up-regulated in mouse peritoneal macrophages in response to stimulation with the TLR4 ligand LPS with a 2-fold increase. The MLL gene encoding the MLL fusion protein is easily activated by ZFP64. ZFP64 is essential for the continuous production of MLL fusion proteins in blood cancer and produces more cancer cells. Since ZFP64 deletion completely and specifically inhibits MLL fusion protein production and leukemia cascade growth, it is an ideal drug target. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag10971 Product name: Recombinant human ZFP64 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 357-681 aa of BC041622 Sequence: ALRIHERIHCTDRPFKCNYCSFDTKQPSNLSKHMKKFHGDMVKTEALERKDTGRQSSRQVAKLDAKKSFHCDICDASFMREDSLRSHKRQHSEYNESKNSDVTVLQFQIDPSKQPATPLTVGHLQVPLQPSQVPQFSEGRVKIIVGHQVPQANTIVQAAAAAVNIVPPALVAQNPEELPGNSRLQILRQVSLIAPPQSSRCPSEAGAMTQPAVLLTTHEQTDGATLHQTLIPTASGGPQEGSGNQTFITSSGITCTDFEGLNALIQEGTAEVTVVSDGGQNIAVATTAPPVFSSSSQQELPKQTYSIIQGAAHPALLCPADSIPD Predict reactive species Full Name: zinc finger protein 64 homolog (mouse) Calculated Molecular Weight: 681 aa, 75 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC041622 Gene Symbol: ZFP64 Gene ID (NCBI): 55734 RRID: AB_3671410 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q9NTW7 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.