Proteintech, 84321-4-RR, CLUH Recombinant monoclonal antibody

Size: 20ul / 100ul The CLUH (84321-4-RR) by Proteintech is a Recombinant antibody targeting CLUH in IF/ICC, ELISA applications with reactivity to human samples 84321-4-RR targets CLUH in IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive IF/ICC detected in: HeLa cells Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500 Background Information Clustered mitochondria homolog (CLUH) is a conserved RNA-binding protein, that binds transcripts encoding proteins involved in the respiratory chain, the tricarboxylic acid (TCA) cycle, and other mitochondrial metabolic pathways. Upon loss of CLUH, target mRNAs are subjected to faster decay, and their respective proteins are decreased in abundance. This leads to alterations in mitochondrial distribution (mitochondrial clustering as the gene name alludes to) mitochondrial cristae integrity, respiratory defects, loss of mtDNA, and decreased activity of TCA cycle enzymes. (PMID: 35559794) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag34275 Product name: Recombinant human CLUH protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1120-1309 aa of BC156940 Sequence: YDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEASRNRDRAEEPMATEPAPAGAPGDLGSQPPAAKDPSPSVQG Predict reactive species Full Name: KIAA0664 GenBank Accession Number: BC156940 Gene Symbol: CLUH Gene ID (NCBI): 23277 RRID: AB_3671863 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: O75153 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.