Proteintech, 84728-4-RR, GP2 Recombinant monoclonal antibody

Size: 20ul / 100ul The GP2 (84728-4-RR) by Proteintech is a Recombinant antibody targeting GP2 in WB, ELISA applications with reactivity to human, mouse, rat samples 84728-4-RR targets GP2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information Pancreatic secretory granule membrane major glycoprotein (GP2) is the most abundant membrane component of zymogen granules secreted by pancreatic acinar cells (PMID: 8190715). GP2 associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. It is released from the membrane of mature zymogen granules by an enzymatic mechanism (PMID: 2011597). GP2 plays a role in defense against adhesive and invasive commensal bacteria during intestinal inflammation (PMID: 33594081). GP2 is preferentially expressed in acinar cell carcinomas of the pancreas but the glycoprotein can rarely also be expressed in a variety of other tumor entities (PMID: 36137400). The apparent molecular weight of GP2 is 70-100 kDa, which is larger than the calculated molecular weight, due to glycosylation (PMID: 19627615; 30186250). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: glycoprotein 2 (zymogen granule membrane) Calculated Molecular Weight: 59 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: NM_001007240.2 Gene Symbol: GP2 Gene ID (NCBI): 2813 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P55259-1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.