Proteintech, 85377-1-RR, ERLIN1 Recombinant monoclonal antibody

Size: 20ul / 100ul The ERLIN1 (85377-1-RR) by Proteintech is a Recombinant antibody targeting ERLIN1 in WB, ELISA applications with reactivity to human samples 85377-1-RR targets ERLIN1 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: U-937 cells, HL-60 cells, HepG2 cells, A549 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information ERLIN1, also known as Erlin-1 or SPFH1, stands for "ER lipid raft-associated protein 1." It is a protein-coding gene that plays a significant role in cellular processes, particularly in the endoplasmic reticulum (ER). The ER is a crucial organelle involved in protein synthesis, lipid metabolism, and calcium homeostasis. ERLIN1 is part of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) domain-containing family of proteins, which are often associated with lipid rafts-microdomains within cellular membranes that are enriched in cholesterol and sphingolipids. ERLIN1 is involved in the regulation of protein degradation, particularly through the ER-associated degradation (ERAD) pathway (PMID: 37683630). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag11393 Product name: Recombinant human ERLIN1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 29-346 aa of BC031791 Sequence: GHLAVYYRGGALLTSPSGPGYHIMLPFITTFRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG Predict reactive species Full Name: ER lipid raft associated 1 Calculated Molecular Weight: 346 aa, 39 kDa Observed Molecular Weight: 39 kDa GenBank Accession Number: BC031791 Gene Symbol: ERLIN1 Gene ID (NCBI): 10613 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O75477 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.