Proteintech, 85907-4-RR, GRK6 Recombinant monoclonal antibody

Size: 20ul / 100ul The GRK6 (85907-4-RR) by Proteintech is a Recombinant antibody targeting GRK6 in WB, ELISA applications with reactivity to human samples 85907-4-RR targets GRK6 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: MCF-7 cells, U2Os cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information GRK6 (G Protein-Coupled Receptor Kinase 6) is a member of the G protein-coupled receptor kinase (GRK) family, which plays a crucial role in regulating the activity of G protein-coupled receptors (GPCRs). GRK6 specifically phosphorylates the activated forms of GPCRs, initiating their desensitization, internalization, and signaling events that lead to receptor deactivation. This process is essential for maintaining proper cellular responses to extracellular signals. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag1992 Product name: Recombinant human GRK6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 54-451 aa of BC017272 Sequence: HSLCERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCFLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKL Predict reactive species Full Name: G protein-coupled receptor kinase 6 Calculated Molecular Weight: 66 kDa Observed Molecular Weight: 65 kDa GenBank Accession Number: BC017272 Gene Symbol: GRK6 Gene ID (NCBI): 2870 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P43250 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.