Proteintech, 86144-1-RR, ERCC6 Recombinant monoclonal antibody

Size: 20ul / 100ul The ERCC6 (86144-1-RR) by Proteintech is a Recombinant antibody targeting ERCC6 in WB, ELISA applications with reactivity to human samples 86144-1-RR targets ERCC6 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information ERCC6, also named as CSB, belongs to the SNF2/RAD54 helicase family. It is involved in the preferential repair of active genes. It is presumed DNA or RNA unwinding function. ERCC6 corrects the UV survival and RNA synthesis after UV exposure of Cockayne syndrome complementation group B. Defects in ERCC6 are the cause of Cockayne syndrome type B (CSB) , cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DSC), and UV-sensitive syndrome (UVS). Genetic variation in ERCC6 is associated with susceptibility to age-related macular degeneration type 5 (ARMD5). The antibody is specific to ERCC6. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag18009 Product name: Recombinant human ERCC6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1144-1493 aa of BC127104 Sequence: DESIDEKLGLSYKRERPSQAQTEAFWENKQMENNFYKHKSKTKHHSVAEEETLEKHLRPKQKPKNSKHCRDAKFEGTRIPHLVKKRRYQKQDSENKSEAKEQSNDDYVLEKLFKKSVGVHSVMKHDAIMDGASPDYVLVEAEANRVAQDAPKALRLSRQRCLGAVSGVPTWTGHRGISGAPAGKKSRFGKKRNSNFSVQHPSSTSPTEKCQDGIMKKEGKDNVPEHFSGRAEDADSSSGPLASSSLLAKMRARNHLILPERLESESGHLQEASALLPTTEHDDLLVEMRNFIAFQAHTDGQASTREILQEFESKLSASQSCVFRELLRNLCTFHRTSGGEGIWKLKPEYC Predict reactive species Full Name: excision repair cross-complementing rodent repair deficiency, complementation group 6 Calculated Molecular Weight: 1493 aa, 168 kDa Observed Molecular Weight: 180 kDa GenBank Accession Number: BC127104 Gene Symbol: ERCC6/CSB Gene ID (NCBI): 2074 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q03468 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.