Product Description
Size: 20ul / 100ul
The PLAGL1 (87281-1-RR) by Proteintech is a Recombinant antibody targeting PLAGL1 in WB, ELISA applications with reactivity to human samples
87281-1-RR targets PLAGL1 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HepG2 cells, MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
PLAGL1 (Pleomorphic adenoma gene-like 1) is a crucial zinc-finger transcription factor acting as a tumor suppressor, regulating cell cycle, growth (apoptosis), and embryonic development, particularly involved in pancreatic function and imprinted expression (paternal allele). While its family member PLAG1 is an oncogene in salivary tumors, PLAGL1 often suppresses tumors, though its dysregulation is linked to transient neonatal diabetes mellitus (TNDM) and certain cancers, highlighting its complex role in growth control and metabolic homeostasis.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag23073 Product name: Recombinant human PLAGL1 protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 201-463 aa of BC074814 Sequence: RHTKKTHSQELMKESLQTGDLLSTFHTISPSFQLKAAALPPFPLGASAQNGLASSLPAEVHSLTLSPPEQAAQPMQPLPESLASLHPSVSPGSPPPPLPNHKYNTTSTSYSPLASLPLKADTKGFCNISLFEDLPLQEPQSPQKLNPGFDLAKGNAGKVNLPKELPADAVNLTIPASLDLSPLLGFWQLPPPATQNTFGNSTLALGPGESLPHRLSCLGQQQQEPPLAMGTVSLGQLPLPPIPHVFSAGTGSAILPHFHHAFR Predict reactive species
Full Name: pleiomorphic adenoma gene-like 1
Calculated Molecular Weight: 463 aa, 51 kDa
Observed Molecular Weight: 51 kDa
GenBank Accession Number: BC074814
Gene Symbol: PLAGL1
Gene ID (NCBI): 5325
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: Q9UM63
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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