Proteintech, 87503-1-RR, CD49b Recombinant monoclonal antibody

Size: 20ul / 100ul The CD49b (87503-1-RR) by Proteintech is a Recombinant antibody targeting CD49b in WB, ELISA applications with reactivity to human, mouse, rat samples 87503-1-RR targets CD49b in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: A549 cells, mouse spleen tissue, rat spleen tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Integrins are a large family of α/β transmembrane receptors playing a key role in cell-cell interactions and cell adhesion to the extracellular matrix (PMID: 30374344). CD49b, also known as integrin alpha-2, is a 150 kDa transmembrane glycoprotein expressed on a wide variety of cell types including platelets, megakaryocytes, NK cells, NKT cells, neutrophils, and long-term activated T cells (PMID: 18802064; 2415516). Integrin alpha-2/beta-1 (also known as VLA-2) is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin (PMID: 2557634). It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg10475 Product name: Recombinant mouse ITA2 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011440 of Sequence: \ Predict reactive species Full Name: integrin alpha 2 Observed Molecular Weight: 150-160 kDa Gene Symbol: CD49b Gene ID (NCBI): 16398 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q62469 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.