Product Description
Size: 20ul / 100ul
The CD59b (87593-1-RR) by Proteintech is a Recombinant antibody targeting CD59b in WB, ELISA applications with reactivity to mouse samples
87593-1-RR targets CD59b in WB, ELISA applications and shows reactivity with mouse samples.
Tested Applications
Positive WB detected in: mouse testis tissue, mouse brain tissue
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
CD59, also named as MIC11, MIN1, MIN2, MIN3, MSK21, MIRL, MACIF, HRF20 and 1F5 antigen, is a cell surface molecule glycoprotein with MW 18-25 kDa. It acts as a determinant of proximal-distal cell identity. CD59 acts by binding to the C8 and/or C9 complements of the assembling membrane attack complex (MAC), thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. It is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. CD59b is
a GPI-anchored protein that is functionally active as a membrane attack complex inhibitor, which is expressed selectively in the mouse testis (PMID: 10946279; 11471050).
Specification
Tested Reactivity: mouse
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Eg7565 Product name: Recombinant mouse CD59b protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 24-104 aa of NM_181858.1 Sequence: LKCYNCLDPVSSCKINTTCSPNLDSCLYAVAGRQVYQQCWKLSDCNSNYIMSRLDVAGIQSKCCQWDLCNKNLDGLEEPNN Predict reactive species
Full Name: CD59b antigen
Calculated Molecular Weight: 14 kDa
Observed Molecular Weight: 18 kDa
GenBank Accession Number: NM_181858.1
Gene Symbol: Cd59b
Gene ID (NCBI): 333883
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P58019
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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