Proteintech, 98079-1-RR, Anti-Human VCAM-1/CD106 Rabbit Recombinant Antibody

Size: 100ug The VCAM-1/CD106 (98079-1-RR) by Proteintech is a Recombinant antibody targeting VCAM-1/CD106 in FC applications with reactivity to human samples 98079-1-RR targets VCAM-1/CD106 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: TNF- α treated HUVEC cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: vascular cell adhesion molecule 1 Calculated Molecular Weight: 81 kDa GenBank Accession Number: NM_001078.4 Gene Symbol: VCAM-1 Gene ID (NCBI): 7412 RRID: AB_3672226 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P19320-1 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.