Proteintech, 98124-1-RR, Anti-Human CD30/TNFRSF8 Rabbit Recombinant Antibody

Size: 100ug The CD30/TNFRSF8 (98124-1-RR) by Proteintech is a Recombinant antibody targeting CD30/TNFRSF8 in FC applications with reactivity to human samples 98124-1-RR targets CD30/TNFRSF8 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: PHA treated human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD30, also known as TNFRSF8 or Ki-1, is a transmembrane glycoprotein belonging to the tumor necrosis factor receptor superfamily. It is composed of an extracellular domain with six cysteine-rich repeats, a transmembrane segment, and an intracellular domain (PMID: 1310894). CD30 is expressed on a small subset of activated T and B lymphocytes, and a variety of lymphoid neoplasms, with the highest expression in classical Hodgkin's lymphoma and anaplastic large cell lymphoma (PMID: 9826579; 28885612). The CD30 ligand (CD30L or CD153) is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily (PMID: 8701986). Signal transduction of CD30/CD30L utilizes signal transducers, TNFR-associated factors (TRAF1, 2, 3 and 5) (PMID: 9826579). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: tumor necrosis factor receptor superfamily, member 8 Calculated Molecular Weight: 64 kDa GenBank Accession Number: NM_001243 Gene Symbol: CD30 Gene ID (NCBI): 943 RRID: AB_3672271 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P28908 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.