Proteintech, 98149-1-RR, Anti-Human IL-12RB1/CD212 Rabbit Recombinant Antibody

Size: 100ug The IL-12RB1/CD212 (98149-1-RR) by Proteintech is a Recombinant antibody targeting IL-12RB1/CD212 in FC applications with reactivity to human samples 98149-1-RR targets IL-12RB1/CD212 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: anti-CD3/CD28 treated human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information Interleukin-12 receptor subunit beta-1 (IL-12RB1), also named as CD212, is a 662 amino acid protein, which contains 5 fibronectin type-III domains and belongs to the type I cytokine receptor family. IL-12RB1 localizes in the membrane and functions as an interleukin receptor which binds IL-12 with low affinity and is involved in IL-12 transduction. Associated with IL-12RB2 it forms a functional, high affinity receptor for IL-12. It can also associate with IL23R to form the interleukin-23 receptor which functions in IL-23 signal transduction probably through activation of the Jak-Stat signaling cascade. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: interleukin 12 receptor, beta 1 Calculated Molecular Weight: 662 aa, 73 kDa GenBank Accession Number: BC029121 Gene Symbol: IL12RB1 Gene ID (NCBI): 3594 RRID: AB_3672294 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P42701 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.