Proteintech, 98171-1-RR, Anti-Human Integrin alpha-5/CD49e Rabbit Recombinant Antibody

Size: 100ug The Integrin alpha-5/CD49e (98171-1-RR) by Proteintech is a Recombinant antibody targeting Integrin alpha-5/CD49e in FC applications with reactivity to human samples 98171-1-RR targets Integrin alpha-5/CD49e in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha-5 (ITGA5, also known as CD49e), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: integrin, alpha 5 (fibronectin receptor, alpha polypeptide) Calculated Molecular Weight: 115 kDa GenBank Accession Number: BC008786 Gene Symbol: Integrin alpha 5 Gene ID (NCBI): 3678 RRID: AB_3672314 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P08648 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.