Proteintech, 98189-1-RR, Anti-Human E-selectin/CD62E Rabbit Recombinant Antibody

Size: 100ug The E-selectin/CD62E (98189-1-RR) by Proteintech is a Recombinant antibody targeting E-selectin/CD62E in FC applications with reactivity to human samples 98189-1-RR targets E-selectin/CD62E in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: TNF alpha treated HUVEC cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information E-selectin, also known as CD62E or ELAM-1, is a member of the selectin family of adhesion molecules that also includes L-selectin and P-selectin. E-selectin is an inducible endothelial cell surface molecule. Its expression on endothelial cells is transcriptionally upregulated by various proinflammatory substances such as IL-1, TNFα and lipopolysaccharide (LPS). Besides, it can be secreted by endothelial cells, and can be detected in a soluble form (sE-selectin) in serum. During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. (PMID: 2827173; 1382417; 8943958) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: selectin E Calculated Molecular Weight: 610 aa, 67 kDa GenBank Accession Number: BC142711 Gene Symbol: CD62E Gene ID (NCBI): 6401 RRID: AB_3672328 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P16581 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.