Proteintech, 98238-1-RR, Anti-Human KIM-1/HAVCR1 Rabbit Recombinant Antibody

Size: 100ug The KIM-1/HAVCR1 (98238-1-RR) by Proteintech is a Recombinant antibody targeting KIM-1/HAVCR1 in FC applications with reactivity to human samples 98238-1-RR targets KIM-1/HAVCR1 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: HuH-7 cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information Kidney injury molecule 1 (KIM-1), also known as Hepatitis A virus cellular receptor 1 (HAVCR1), CD365, or T-cell immunoglobulin and mucin domain 1 (TIM-1), is a class I integral membrane glycoprotein, with an ectodomain containing Ig-like domain and a mucin domain. KIM-1 acts as a membrane receptor for hepatitis A virus (HAV) (PMID: 9658108; 8861957). KIM-1 provides a costimulatory signal for T cell activation and inhibits the development of peripheral tolerance (PMID: 16284246; 15793575). KIM-1 may be involved in the regulation of asthma and allergic diseases (PMID: 14534576). It has been reported that KIM-1 is shed into urine after acute kidney damage and is a marker of renal tubular injury (PMID: 14600030). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: hepatitis A virus cellular receptor 1 Calculated Molecular Weight: 39kDa GenBank Accession Number: NM_001173393.3 Gene Symbol: HAVCR1 Gene ID (NCBI): 26762 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q96D42 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.