Proteintech, 98404-1-RR, Anti-Mouse CD268/BAFF-R Rabbit Recombinant Antibody

Size: 100ug The CD268/BAFF-R (98404-1-RR) by Proteintech is a Recombinant antibody targeting CD268/BAFF-R in FC applications with reactivity to mouse samples 98404-1-RR targets CD268/BAFF-R in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453). Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg1840 Product name: Recombinant Mouse BAFFR/TNFRSF13C protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 10-71 aa of NM_028075.2 Sequence: SQRSRDSSVPTQCNQTECFDPLVRNCVSCELFHTPDTGHTSSLEPGTALQPQEGSALRPDVA Predict reactive species Full Name: tumor necrosis factor receptor superfamily, member 13c Calculated Molecular Weight: 19 kDa GenBank Accession Number: NM_028075.2 Gene Symbol: Tnfrsf13c Gene ID (NCBI): 72049 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9D8D0-1 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.