Proteintech, 98534-2-RR, Anti-Human PLXNC1 Rabbit Recombinant Antibody

Size: 100ug The PLXNC1 (98534-2-RR) by Proteintech is a Recombinant antibody targeting PLXNC1 in FC applications with reactivity to human samples 98534-2-RR targets PLXNC1 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs, Transfected CHO cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information PLXNC1 (Plexin-C1) is a semaphorin receptor that bridges extracellular guidance cues to intracellular GTPase signaling, influencing cell adhesion, migration, and immune modulation. Predominantly expressed in neuronal, epithelial, and immune tissues, PLXNC1 regulates axon guidance and inflammatory balance via SEMA7A-dependent pathways. Dysregulated PLXNC1 signaling contributes to cancer progression, immune dysregulation, and neuronal pathologies, highlighting its versatile role in cell communication and morphogenesis. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2721 Product name: Recombinant Human PLXNC1 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 35-944 aa of NM_005761.3 Sequence: ADEPVWRSEQAIGAIAASQEDGVFVASGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRNSLRNGTEVVSCHPQGSTAGVVYRAGRNNRWYLAVAATYVLPEPETASRCNPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYPYNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPACVETGCAWCKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGGRPKENKGNRTNQALQVFYIKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDNLIISHELKGNINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQYREDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPST Predict reactive species Full Name: plexin C1 Calculated Molecular Weight: 176 kDa GenBank Accession Number: NM_005761.3 Gene Symbol: PLXNC1 Gene ID (NCBI): 10154 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O60486 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.