Proteintech, 98620-1-RR, Anti-Human P-cadherin Rabbit Recombinant Antibody

Size: 100ug The P-cadherin (98620-1-RR) by Proteintech is a Recombinant antibody targeting P-cadherin in FC applications with reactivity to human samples 98620-1-RR targets P-cadherin in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: A431 cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. P-cadherin (placental cadherin), also known as CDH3 (cadherin 3), is a classical member of the cadherin superfamily which also include E-, N-, R-, and B-cadherins. Aberrant expression of P-cadherin has been reported in many cancers, including breast, gastric, endometrial, ovarian, and prostate cancer. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg5236 Product name: recombinant human CDH3 protein Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 108-440 aa of NM_001793.5 Sequence: DWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVF Predict reactive species Full Name: cadherin 3, type 1, P-cadherin (placental) Calculated Molecular Weight: 91 kDa GenBank Accession Number: NM_001793.5 Gene Symbol: P-cadherin Gene ID (NCBI): 1001 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P22223-1 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.