Proteintech, 98625-2-RR, Anti-Mouse LEPR Rabbit Recombinant Antibody

Size: 100ug The LEPR (98625-2-RR) by Proteintech is a Recombinant antibody targeting LEPR in FC applications with reactivity to mouse samples 98625-2-RR targets LEPR in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: Transfected CHO cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information Leptin receptor (LEPR) is a protein-coding gene that encodes a receptor for leptin, an adipocyte-specific hormone that regulates body weight and fat metabolism (PMID: 11861497; 16333525). LEPR is involved in various physiological processes, including energy homeostasis, immune function, and hematopoiesis (PMID: 11923481; 25383904). It activates the JAK2/STAT3 signaling pathway, which is crucial for mediating leptin's effects on gene transcription and cellular responses (PMID: 11923481). LEPR also plays a role in the regulation of lipid metabolism, blood pressure, and blood glucose levels (PMID: 29254602). Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2930 Product name: Recombinant Mouse Lepr protein (rFc Tag) (HPLC verified) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 22-839 aa of NM_146146.2 Sequence: LNLAYPISPWKFKLFCGPPNTTDDSFLSPAGAPNNASALKGASEAIVEAKFNSSGIYVPELSKTVFHCCFGNEQGQNCSALTDNTEGKTLASVVKASVFRQLGVNWDIECWMKGDLTLFICHMEPLPKNPFKNYDSKVHLLYDLPEVIDDSPLPPLKDSFQTVQCNCSLRGCECHVPVPRAKLNYALLMYLEITSAGVSFQSPLMSLQPMLVVKPDPPLGLHMEVTDDGNLKISWDSQTMAPFPLQYQVKYLENSTIVREAAEIVSATSLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSSPQVFTTQDVVYFPPKILTSVGSNASFHCIYKNENQIISSKQIVWWRNLAEKIPEIQYSIVSDRVSKVTFSNLKATRPRGKFTYDAVYCCNEQACHHRYAELYVIDVNINISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQRDGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVKAEITVNTGLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPMRGPEFWRKMDGDVTKKERNVTLLWKPLTKNDSLCSVRRYVVKHRTAHNGTWSEDVGNRTNLTFLWTEPAHTVTVLAVNSLGASLVNFNLTFSWPMSKVSAVESLSAYPLSSSCVILSWTLSPDDYSLLYLVIEWKILNEDDGMKWLRIPSNVKKFYIHDNFIPIEKYQFSLYPVFMEGVGKPKIINGFTKDAIDKQQNDAG Predict reactive species Full Name: leptin receptor Calculated Molecular Weight: 131 kDa GenBank Accession Number: NM_146146.2 Gene Symbol: Lepr Gene ID (NCBI): 16847 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P48356-1 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.