Proteintech, 98647-1-RR, Anti-Human IFN-alpha 4/IFNA4 Rabbit Recombinant Antibody

Size: 100ug The IFN-alpha 4/IFNA4 (98647-1-RR) by Proteintech is a Recombinant antibody targeting IFN-alpha 4/IFNA4 in FC (Intra) applications with reactivity to human samples 98647-1-RR targets IFN-alpha 4/IFNA4 in FC (Intra) applications and shows reactivity with human samples. Tested Applications Positive FC (Intra) detected in: Transfected CHO cells Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information IFN-alpha 4 (IFN-α4 or IFNA4) belongs to the type I interferon family, a group of cytokines primarily produced in response to viral infections. As a key player in the innate immune response, IFN-α4 provides the body's first line of defense against pathogens by inducing an antiviral state in neighboring cells. Produced primarily by macrophages, IFN-α4 exerts its antiviral effects by binding to the interferon alpha receptor (IFNAR) on cell surfaces, thereby activating downstream immune signaling pathways . This binding triggers the expression of antiviral proteins, such as a protein kinase and an oligoadenylate synthetase, which inhibit viral RNA replication and enhance natural killer cell cytotoxicity against viruses. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg4962 Product name: Recombinant Human IFNA4 protein (rFc Tag)(HPLC verified) Source: mammalian cells -derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 24-189 aa of BC113642 Sequence: CDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFGFPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD Predict reactive species Full Name: interferon, alpha 4 GenBank Accession Number: BC113642 Gene Symbol: IFNA4 Gene ID (NCBI): 3441 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P05014 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.