Proteintech, APC-FcA98175, FcZero-rAb™ APC Anti-Human CXCR4/CD184 Rabbit Recombinant Antibody

Size: 100tests The CXCR4/CD184 (APC-FcA98175) by Proteintech is a Recombinant antibody targeting CXCR4/CD184 in FC applications with reactivity to human samples APC-FcA98175 targets CXCR4/CD184 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension Background Information C-X-C chemokine receptor type 4 (CXCR4, also known as CD184) is a widely expressed G protein-coupled seven-transmembrane receptor. CXCL12/SDF-1 is the biological ligand for CXCR4. The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription (PMID: 20484021). CXCR4 also functions as a coreceptor for HIV-1 entry (PMID: 9427609). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: chemokine (C-X-C motif) receptor 4 Calculated Molecular Weight: 352 aa, 40 kDa GenBank Accession Number: BC020968 Gene Symbol: CXCR4 Gene ID (NCBI): 7852 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Form: Liquid Purification Method: Protein A purification UNIPROT ID: P61073 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.