Revvity, ES-036-A, AequoScreen Human Adrenergic α Cell Line, CHO-K1 Cells

Overview
Revvity's AequoScreen double transfected cell lines are provided in two vials of frozen cells, each containing ∽2.5 x 106 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available each cell line.
AequoScreen technology is a generic GPCR technology that can be used with Gs, Gi, and Gq-coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of resulting flash luminescence signal.
Features:

Fully automatable and miniaturizable to 1536
Enables reduction in reagents and consumable costs
High signal to background ratio enabling detection of agonists, antagonists and allosteric modulators
Robust assay (Z′, CV values, solvent resistance)
Reduces number of false positives from autofluorescent compounds in screening libraries
Option to work with cells in suspension to increase throughput
Amenable use with calcium coupled ion channels and tyrosine kinase receptors

Revvity’s AequoScreen cell lines require accepted cell line Terms and Conditions prior to order processing. Additional agreement needed for commercial use. Please use link above to accept Terms and Conditions or to request an agreement for commercial use.
Application-Drug Discovery & Development
Brand-AequoScreen
G-Alpha Natural Receptor-G q /G 11
Host Cell Line-CHO-K1
Host Species-Human
Product Group-Cell Line
Receptor-Adrenergic
Second Messenger Release-Calcium flux
Shipping Conditions-Shipped in Dry Ice
Special Ordering Information-Requires accepted Terms and Conditions. Additional agreement needed for commercial use.
Target Class-GPCR
Therapeutic Area-Central Nervous System Metabolic
Unit Size-5 million
Validation-Binding Calcium Luminescence