Revvity, NEX312050UC, AB-MECA, [ I]-(4-Amino-3-[ I]iodobenzyl-5`-N-)-, 50µCi

Overview
50 µCi Quantities of AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)- are available for your research.
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX312:

Haeusler, D., Grassinger, L., Fuchshuber, F. et al. (2015), Hide and seek: a comparative autoradiographic in vitro investigation of the adenosine A3 receptor, Eur J Nucl Med Mol Imaging, 42: 928-939.
Ongini, E., Dionisotti, S., Gessi, S. et al. (1999), Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors, Naunyn-Schmiedeberg's Arch Pharmacol, 359: 7-10. Molecular Weight-523
Specific Activity-2200 Ci/mmol (81.4 TBq/mmol)
CAS Number-152918-26-8

Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-Methanol
Detection Modality-Radiometric
Fresh Lot Days-Second Monday of each month
Label Position-Nominally Labeled
Molecular Formula-C18H21N7O4
Packaging-NENSure vial
Radioisotope-125 I
Receptor-Adenosine
Shipping Information-Shipped Ambient
Shipping Conditions-Shipped Ambient
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions-4°C
Therapeutic Area-Cardiovascular CNS & Neurologic Inflammation Metabolic Disorders
Unit Size-50 µCi