Waters, 186009441, BioResolve SEC mAb Column, 200Å, 2.5 µm, 7.8 x 300 mm, 1/pk

Primarily used for legacy methods. If you are developing a new method, please consider our newer technology XBridge Premier Protein 250Å SEC and ACQUITY Premier Protein 250Å SEC Columns for superior recovery, separation, and resolution. The BioResolve SEC mAb Guard is specifically designed to extend the life of the BioResolve SEC mAb Columns. It effectively traps inadvertent injection of insoluble particulates and/or excipients sometimes present in samples and/or SEC eluents. The BioResolve SEC mAb Guard will not degrade the separation of mAb aggregates.

Specifications
Chemistry: SEC
Separation Mode: SEC
Particle Substrate: Hybrid
pH Range Min: 2.5 pH
pH Range Max: 8 pH
Temperature Limits: 60 C
Maximum Pressure: 6,500 psi (448 Bar)
Endcapped: No
Bonding Technology: Diol (OH)
Silanol Activity: Low
Molecular Weight Range Min: 10000
Molecular Weight Range Max: 450000
Particle Shape: Spherical
Particle Size: 2.5 µm
Endfitting Type: Waters
Pore Size: 200 Å
QC Tested: Protein
Format: Online Column
Packing Solvent: 10% acetonitrile/90% 25 mM sodium phosphate pH 7.0 + 100 mM KCl
Surface Area: 220
System: UHPLC, UPLC, HPLC
Particle Technology: BEH
Technique: LC
USP Classification: L20, L33, L59
Inner Diameter: 7.8 mm
Length: 300 mm
Carbon Load: 12 %
eCord: Yes
UNSPSC: 41115711
Application: Protein
Brand: BioResolve
Product Type: Columns
Units per Package: 1 pk

Additional Information
BioResolve SEC mAb Column, 200Å, 2.5 µm, 7.8 x 300 mm, 1/pk Specific analytical challenges apply to the analysis of mAb-based therapeutic drugs, but those challenges can be easily conquered with the help of the BioResolve SEC mAb Column. This bioseparations column is equipped with incredible features to make your life easier in the lab, plus it offers a wide and usable pH range so you can use varying analytes while maintaining chemical and mechanical stability. What’s more, the BioResolve SEC mAb Column can be used on any LC system, including UHPLC and UPLC. This is just another way we’re providing mAb separation tools that don’t compromise on performance. Biological separations isn’t all that the BioResolve SEC mAb Column can perform, though. Thanks to the unique selectivity for mAbs, this column can also be used for protein separations. But first, before you purify your samples and prepare them for separation, make sure to check your LC-MS system for proper performance. We even make system benchmarking easier, as the Waters Size Variant Standard is included with this column at no extra charge. Add Ethylene-Bridged Hybrid (BEH) particle technology and it’s easy to see why the BioResolve SEC mAb Column is chosen by scientists across the globe for its selectivity and performance. What was the BioResolve SEC mAb Column designed to provide? For one thing, this column is designed to provide highly reproducible quantitation of monoclonal antibody monomers from both high molecular weight aggregates and low molecular weight fragments. This column must also undergo strict QC processes and testing before being shipped to you, so you only receive separation tools that are ready to go right out of the box. Purposely designed for organizations that develop mAb-containing drugs, the BioResolve SEC mAb Column address internal and regulatory concerns regarding biotherapeutics. But just as important as meeting regulatory concerns, you need to protect this column from possible contamination over time. To do so, we recommend purchasing the BioResolve SEC mAb Guard . This guard column seamlessly incorporates into your existing workflow to trap contaminants and remove them from the mobile phase stream. No matter if you need a BioResolve SEC mAb Column or something else in the LC-MS market, you’ll find exactly what you need at Waters Corporation. But did you know that we also offer lab informatics and workflow solutions to improve lab efficiency? Shop lab equipment to discover everything we have to offer.

FAQ
What’s the BioResolve SEC mAB Column’s Molecular Weight Range? The BioResolve SEC mAB Column offers a range of 10,000-450,000 for molecular weight.