Waters, 186010747, Waters Lipid Conjugated ASO LC-MS Standard

The Waters Lipid Conjugated ASO LC-MS Standard is a 5 nmole quantity of a 16 residue gapmer antisense oligonucleotide (ASO) containing a fully phosphorothioated backbone, a 5’ palmitate modification and methoxy ethyl modified termini. Its sequence is provided in its manual and on its certificate of analysis.  It has a negative control sequence that does not have any homology with mammalian genes. The 5’ modification is created from the use of a 5'-Palmitate-C6 CE phosphoramidite. This is a standard that is to be used as a performance check and potential system suitability standard for oligonucleotide extractions with the OligoWorks SPE Kits as well as LC-UV and LC-MS analyses, as performed with IP-RPLC, HILIC or IEX separations.

Specifications
Separation Mode: Reversed Phase
Detection Method: MS
Formulation: Solid
Storage Condition: -20C +/- 10C (Freezer)
System Type: LC/MS
Instrument: UPLC, UHPLC, HPLC
Shelf Life: 24 Months
Shelf life upon reconstitution: 1 Week
Shipping Condition: Ambient
Tolarence: +/- 20%
Type: System Performance
UNSPSC: 41116107
Application: Oligonucleotide, Gene Therapeutics
Brand: Waters
Product Type: Standards
Units per Package: 1 pk