Sartorius, 1422-050, CellGenix® rh Activin A (Preclinical Grade)

Top Features for Recombinant Human Activin A:
Optimal use for differentiation of iPSCs and ESCs into definitive endoderm
ADCF Level 2
High purity to ensure the safety of your process
Available in two different grades (Preclinical and GMP grade)

CellGenix® Recombinant Human Activin A is an animal-derived component-free product. It is produced in a dedicated animal-free GMP facility. Activin A is used in the cell and gene therapy space to promote differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into definitive endoderm, and for the maintenance and self-renewal of pluripotent stem cells (PSCs).
GMP grade: CellGenix® GMP rh Activin A is produced following applicable GMP guidelines and allows for the safe use in accordance with USP Chapter <1043>, Ph. Eur. General Chapter 5.2.12 and ISO 20399:2022.
CellGenix® GMP cytokines are provided with documented evidence of purity, potency, consistency and stability. In combination with our expert regulatory and technical support this will help simplify your raw material qualification and validation efforts.
Expiry: ≥ 6 months from date of shipping
Preclinical grade: Designed to meet the demands of translational research, CellGenix® Preclinical cytokines are ideal to bridge the gap between the lower quality of research grade and the higher costs of GMP grade materials.
Expiry: 3 years from date of shipping
For the exact expiry date and the batch specific activity, please refer to the Certificate of Analysis on the My Sartorius Portal.
Safety Data Sheets (SDSs) are available on request.

Specifications
Applications:
Application Area: Cell & gene therapy; Immunology
Cell Type: ESC/iPSC; Organoids
Intended Use: Preclinical ex vivo use

Biological Information:
Activity: ≥ 0.5 x 106 IU/mg

Compliance Information:
Origin: Animal-Component Free
Quality Grade: Preclinical

Features:
Carrier-Protein Free: Yes

Physicochemical Information:
Endotoxin: ≤ 1 EU/µg
Expression System: E. coli
Formulation: Lyophilized from a 0.2 µm-filtered solution containing 20 mM glycine, 150 mM sodium chloride and 3% mannitol, pH 9.5

Product Information:
Brand: CellGenix®
Package Type: Vial
Size: 50 µg

Sterility/Purity:
Delivery Condition: Sterile
Purity: ≥ 95%

Weight:
Molecular Weight (kDa): 26.2 kDa