Cytiva HyClone — Cell Culture Media, Sera & Process Liquids

HyClone is Cytiva’s upstream portfolio for consistent, scalable cell culture—covering sera, basal and chemically defined media, feeds, buffers, and process liquids. Its focus on lot traceability, documentation, and supply continuity helps you stabilize growth and productivity from R&D flasks to perfusion and fed-batch bioreactors.

In academic labs, CDM screening, or GMP suites, HyClone emphasizes reproducible performance and clean paperwork. With clear specifications, lot-to-lot data, and cold-chain options, you can qualify inputs once, then carry your recipe forward through scale-up without constantly revalidating core materials.

Core Product Categories

Use this map to match your upstream goal—growth, productivity, or consistency—to the right class of materials. Start from cell line and mode (batch/fed-batch/perfusion), then choose media/feeds and supporting liquids.

• Sera (Research & Qualified Grades)
  Representative items: Fetal Bovine Serum (FBS), species-specific sera; heat-inactivation and low-endotoxin options
  Use cases: Early research, hard-to-adapt lines, supplementing legacy processes

• Basal & Chemically Defined Media (CD/SFM)
  Representative items: Basal media for CHO/HEK/Hybridoma; chemically defined and serum-free formulations
  Use cases: Process development, regulatory pathways requiring tighter composition control

• Feeds & Supplements
  Representative items: Concentrated feeds, hydrolysates/peptones, selective supplements
  Use cases: Fed-batch productivity gains, titer stability, nutrient balancing

• Buffers & Process Liquids
  Representative items: PBS/DPBS, balanced salts, neutralizing and equilibration buffers, cleaning/conditioning liquids
  Use cases: Media prep, column equilibration/flush, in-process conditioning steps

• Water & Ancillary Upstream Reagents
  Representative items: High-purity water for media/buffer prep, pH/OSM support reagents
  Use cases: Recipe make-up, reproducible prep across batches and suites

• Documentation & Lot Services
  Representative items: CoA/SDS/DoC packs, lot reservation/retains, side-by-side evaluation support
  Use cases: Tech transfer, audit readiness, change control and comparability

More from Cytiva

For a complete, end-to-end path beyond upstream culture, Cytiva’s other classic brands cover purification and clarification—available via Iright with the same documentation support.

• ÄKTA — chromatography systems, columns, and UNICORN software for method development to manufacturing.

• Whatman — membranes, syringe filters, and papers for sample prep and clarification.

• Pall — single-use assemblies and bioprocess filtration from depth to sterilizing-grade and virus steps.