Sartorius, 3021860630W-BSW, Sartocube® Cassette | Hydrosart® | 0.45µm | 3m²

Membrane Material: Hydrosart®
Effective Filtration Area: 3m²
Pore Size: 0.45 µm
Screen Type: Wide Spacer

Sartocon Hydrosart® cassettes are characterized by ultra-low protein adsorption, easy cleaning, higher yields, and long product life. Even with repeated use, Hydrosart® ultrafiltration membrane maintains it’s performance without fouling or loss of retention.
Sartocon® cassettes are self-sealing, feature low extractables and the enlarged feed and retentate ports lower system pressure drops.
Sartocon® cassettes are ideally combined with Sartorius Sartocon holders and systems.
Hydrosart® Membrane
Hydrosart® high performance membrane is a stabilized cellulose-based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane depyrogenation can be accomplished by using NaOH even at elevated temperatures. These features make Hydrosart® an ideal membrane for biological applications.
Flow Channel Geometry
The Sartocon® family is available in two flow channel geometry versions. E-Screen filters are dominantly used for protein concentrations up to above 20% as well as viscosity conditions greater than 3 cp. ECO-Screen devices mainly used for water based protein solutions of below 20% protein concentration as well as lower than 3 cp viscosity allow economical optimized filtration runs.
Available Sizes and Cut-Offs
Sartorius Sartocon® and Sartocube® TFF cassettes are available for pilot- and production scale, and in Sartocon® Slice as well as Sartocon® Slice 200 format for reduced volume handling.
Cut-Offs:
E-screen: 2 | 5 | 10 | 30 | 100 | 300 kDa | 0.2µm | 0.45µm
ECO screen: 10 | 30 | 100 | 300 kDa
Regulatory Compliance
All product contact materials have passed the current USP Biological Test and Cytotoxicity Test. All materials are BSE and TSE free. The filtrate meets or exceeds the currently valid USP and EP for sterile Water for Injection, with respect to extractable substances, oxidizable substances and Bacteria Endotoxins.

Specifications
Applications:
Industry: Pharma / Biotech

Compliance Information:
Bacterial Endotoxins: < 0.18 EU/mL as determined by the LAL test
Biological Reactivity: All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
Extractables: The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions:
Filtration Area: 3 m²
Flow Channel Geometry: Microfilter Wide Spacer

General Specifications:
Cassette Format: Sartocube Cassettes
Filter Class: Microfilter
Filter Format: Cassettes

Materials of Construction:
Integral Frame: Polyvinylidene fluoride (PVDF)
Membrane Material: Hydrosart®
Sealing Compound: Silicone White (High chemical resistance)
Spacer: Polypropylene (PP)

Operating Conditions:
Maximum Inlet Pressure: 4 bar
pH Stability: pH 2 – 14

Physicochemical Information:
Non-Fiber Releasing: This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Pore Size: 0.45 µm

Product Information:
Brand: Sartocube®
Pack Size: 1
Type: 0.45µm | Hydrosart® | 3m²