Sartorius, 96IEXS42D2HSS, Sartobind® S Capsule 400 mL with 4 mm bed height

Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.
Applications:
The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).
Benefits:
The Sartobind S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.
High speed host cell protein removal up to 30 bed volumes/ min
Aggregate removal
Easy to use:
Plug and play devices from 0.08 ml to 5 l
Can be used like a filter
Flow rate up to 30 bed volumes/min
Disposable or re-usable

Specifications
Applications:
Application: Polishing

Compliance Information:
Biological Reactivity: All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).

Connections (Physical):
Connector(s): Inlet: 1 ½" Sanitary | Outlet: 1 ½" Sanitary

Dimensions:
Bed Height: 4 mm
Dimensions WxDxH: 10 × 57 cm
Membrane Area: 1.46 m²

Features:
Reusable: Yes

Materials of Construction:
Housing Material: Polypropylene (PP)
Materials of Construction: Polypropylene; Polyester
Membrane Material: Stabilized reinforced cellulose

Operating Conditions:
Maximum Operating Pressure: 0.4 MPa
Maximum Venting Pressure: 0.5 bar, 0.05 MPa, 7 psi
Recommended Flow Rate: 8 L/min
pH Stability: pH 3 – 14 (short term), pH 4 – 13 (long term)

Physicochemical Information:
Bed Volume: 400 mL
Ligand: Sulfonic acid
Ligand Density: 2 – 5 µeq/cm²
Pore Size: 3 – 5 µm
Reference Protein: Lysozyme
Thermal Stability: Sartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.
Typical Dynamic Binding Capacity 10% per unit: 10.2 g
Void Volume: 1.08 L

Product Information:
Brand: Sartobind® S
Membrane Adsorber Format: Capsules
Membrane Type: Strong cation exchanger
Pack Size: 1
Type: Membrane adsorber
What you receive: 1 capsule; 1 operating instruction; 1 certificate