Waters, 186005303, ACQUITY UPLC CSH C18 VanGuard Pre-column, 130Å, 1.7 µm, 2.1 mm X 5 mm, 3/pk

ACQUITY CSH C18 columns were designed to provide alternate selectivity compared to other reversed-phase UPLC columns. These ultra-efficient columns overcome peak shape asymmetry and poor loading capacity for basic compounds, column bleed, and rapid mobile-phase re-equilibration. The VanGuard pre-column connects directly to the inlet of the ACQUITY UPLC column which minimizes extra columns volumes and reduces leaking by eliminating additional connections.

Specifications
Chemistry: C18
Separation Mode: Reversed Phase
Particle Substrate: Hybrid
pH Range Min: 1 pH
pH Range Max: 11 pH
Maximum Pressure: 18000 psi (1240 Bar)
Endcapped: Yes
Silanol Activity: Low
Particle Shape: Spherical
Particle Size: 1.7 µm
Endfitting Type: Direct-Connect
Pore Size: 130 Å
Format: VanGuard Pre-column
Surface Area: 185
System: UPLC, UHPLC
Particle Technology: CSH
USP Classification: L1
Inner Diameter: 2.1 mm
Length: 5 mm
Carbon Load: 15 %
UNSPSC: 41115709
Brand: ACQUITY UPLC
Product Type: Guards
Units per Package: 3 pk

Additional Information
ACQUITY UPLC CSH C18 VanGuard Pre-column, 130Å, 1.7 µm, 2.1 mm X 5 mm, 3/pk Ideally suited for the physical and chemical protection of ACQUITY UPLC columns, VanGuard Pre-columns are specifically engineered to preserve the lifetime of these columns without negatively impacting their separation performance. The ACQUITY UPLC CSH C18 VanGuard Pre-Column is designed to be compatible with UPLC pressures up to 18,000 psi (1241 bar) in application areas where chemical and/or particulate contamination can shorten the lifetime of UPLC Columns. With a 2.1 mm ID x 5 mm length, ultra-low volume design, this pre-column efficiently protects performance while offering an approach to higher efficiency, greater resolution, and increased throughput. This is possible because the same stationary phases and column frits are used as in ACQUITY UPLC CSH C18 Column, 130Å, 1.7 µm, 2.1 mm X 50 mm, 1/pk . The ACQUITY UPLC CSH C18 VanGuard Pre-column connects directly to the inlet of ACQUITY UPLC columns, minimizing extra column volumes and mobile-phase leaks that may have resulted if additional connections were needed. This makes them the perfect lab equipment for demanding application areas that analyze complex, unpredictable, and challenging samples on a routine basis. Including bioanalysis, food and beverage, natural products, environmental, and industrial chemical samples, these separations can have a negative impact on column lifetime if the appropriate sample preparation and cleanup procedures are not implemented, calling for a reliable pre-column that eliminates leaks and connection voids. Benefit from the CSH Technology present in ACQUITY CSH C18 columns, including alternate selectivity compared to other reversed-phase columns, overcoming peak shape asymmetry, poor loading capacity in basic compounds, column bleed, and rapid mobile phase re-equilibration.

FAQ
What Is CSH Technology? CSH Technology is based on the 1.7 µm Charged Surface Hybrid particle designed by Waters as their third generation of hybrid particle technology. CSH incorporates a low-level surface charge, improving sample loadability and peak asymmetry in low ionic strength mobile phases. This is done while maintaining mechanical and chemical stability inherent in existing BEH particle technology.
Advantages of CSH Technology in UPLC columns include superior peak shape, increased loading capacity, improved reproducibility, exceptional stability across the pH range, and rapid column equilibration after changing mobile-phase pH.
CSH particle technology is available in both UPLC and HPLC particle sizes and allows for seamless transfer between platforms.