Agilent Chromatography Vials, Caps & Septa | Secure Sample Handling for HPLC & GC Systems

Agilent offers a comprehensive range of chromatography vials, caps, and septa designed to support accurate, reproducible results in analytical laboratories. These consumables are engineered for compatibility with high-performance chromatography systems, ensuring secure sample handling, minimal contamination risk, and optimal instrument performance.

What Are Chromatography Vials, Caps & Septa Used For?

Agilent chromatography vials, caps, and septa are critical components used in liquid chromatography (HPLC/UHPLC) and gas chromatography (GC) workflows. They serve as primary sample containers, protecting analytical samples from contamination, evaporation, or chemical degradation.

These components are essential in enabling:

• Secure containment of liquid or volatile samples for quantitative analysis.
• Chemical compatibility with a broad range of solvents and analytes.
• Precise autosampler alignment and injection for high-throughput operations.
• Consistent sealing to preserve sample integrity over time.

Key Features and Technical Advantages

Agilent’s vials, caps, and septa are developed under stringent manufacturing standards to ensure performance consistency across regulated and research environments.

• High dimensional precision – Guarantees optimal autosampler compatibility and robotic handling.
• Chemical resistance and low background – Septa materials (e.g., PTFE/silicone, butyl rubber) resist leaching and degradation by organic solvents.
• Leak-proof sealing – Crimp, screw, and snap caps offer varying levels of seal tightness for different analysis needs.
• Pre-cleaned and certified options – Available for sensitive applications including LC/MS and trace-level GC analysis.
• Compliance-ready – Products meet industry standards for GLP/GMP laboratories.

Available Vial, Cap, and Septa Configurations for Chromatography Applications

Industry Applications for Agilent Sample Vials, Caps, and Septa

Agilent vials and closures are widely used in laboratories across multiple sectors that rely on high-precision chromatographic analysis:

• Pharmaceutical and Biotech – Sample preparation for drug development, stability testing, and impurity profiling.
• Environmental Testing – Analysis of contaminants and organic compounds in water, soil, and air samples.
• Food and Beverage Safety – Monitoring of additives, preservatives, and pesticide residues.
• Clinical and Forensic – Biological sample handling in toxicology, metabolomics, and forensic studies.
• Chemical and Petrochemical – Quality control and R&D applications involving organic solvents and hydrocarbons.

Chromatography Vial and Cap Selection – Frequently Asked Questions

Q1: How should I choose between screw, snap, and crimp caps?

Screw caps offer ease of use and compatibility with most autosamplers. Crimp caps provide the most secure seal for volatile or hazardous samples. Snap caps are best suited for manual injections or short-term storage.

Q2: Which septum material is most suitable for LC/MS applications?

PTFE/silicone septa are typically recommended for LC/MS due to their chemical resistance and low background extractables.