Abcam, ab108444, Anti-P2Y13 antibody [EPR3698]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal P2Y13 antibody. Suitable for WB and reacts with Human samples. Cited in 4 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR3698,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.05% Sodium azideConstituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 0.1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Stable for 12 months at -20°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
P2Y13 also known as P2RY13 is a G-protein coupled receptor part of the P2Y receptor family. It has a mass of approximately 42 kDa. Functionally P2Y13 recognizes extracellular nucleotides like ADP and initiates signaling cascades thereafter. This receptor is expressed in various tissues including the brain liver and immune cells. In the nervous system it plays a role in neurotransmission and might influence neuronal functions.
Biological function summary
P2Y13 participates in purinergic signaling. This pathway influences cellular responses and plays a role in multiple physiological processes. P2Y13 is not known to form part of a larger receptor complex but interacts with G-proteins to transmit signals within the cell. Its activity helps regulate lipid metabolism and influences energy homeostasis in the body.
Pathways
P2Y13 is involved in the ADP-mediated signaling pathway a critical component in the regulation of cholesterol and lipid metabolism. It interacts with proteins like G-protein subunits to activate downstream signaling pathways. In the broader context of these pathways P2Y13 supports cellular processes such as energy balance and detoxification of substances.
P2Y13 has been connected with cholesterol imbalance and related metabolic disorders. Its role in lipid homeostasis indicates it might be relevant in atherosclerosis a condition characterized by lipid accumulation in the arteries. P2Y13 also associates with neurological disorders due to its presence and role in neural tissues. It is connected to other purinergic receptors like P2Y12 in these disease contexts which collectively contribute to disease progression through dysregulated purinergic signaling.